Pharma Consulting
Conventional pharmaceutical formulations
- Support for all the problems related to conventional pharmaceutical forms, trying to promote an improvement both from a technological and a productive point of view;
- characterization of formulations with the possibility of reformulation and / or contribution of improvements to existing commercial products and present in the pipeline of companies;
- Formulation of nutraceutical products;
- Evaluation of the characteristics of compressibility and densification of powders and granulates
- Determination of mucoadhesive capacities of solid and semi-solid pharmaceutical forms
- Study of rheological characteristics of fluids, gels and semi-solid materials in general
Advanced Drug Delivery Systems
- support in the development of innovative pharmaceutical forms, which employ advanced carrier systems capable of increasing the therapeutic efficacy and reducing the side effects of different types of drugs. Such as, for example, classic drugs of chemical origin, but also new biotechnological therapeutic agents such as proteins, antibodies and vaccines
- Techniques of solubilization of active ingredients insoluble in water (inclusion complexes with cyclodextrins and solid dispersions)
- Formulation of microparticles and microcapsules
- Formulation of controlled release systems
- Synthesis and characterization of self-assembling and thermo-gelifying properties of block/sensioactive copolymers and their use for controlled release of proteins
Raw materials
- consulting and sourcing of innovative and high quality raw materials for the preparation of pharmaceutical forms
- Thermal analysis of polymeric materials
Design of Experiment (DoE)
- consultancy concerning the problems related to the industrial scale-up of the main pharmaceutical forms most commonly used, allowing the prototyping of the dosage form and the characterization of the prototype in terms of quality and scale-up of industrial production
- This aspect is supported at a statistical level through the creation of suitable experimental plans
Galenics in pharmacy
- Control on the production process and on the final formulation of all the preparations prepared in the galenical laboratory, whether pharmaceutical, nutraceutical or cosmetic. The support to the preparation and the controls carried out by PFC will be a guarantee of effectiveness and quality both for the formulator himself and for the patient who will use it.
- The possibility that pharmacies have to produce magistral and officinal galenic preparations, sterile or not, will be encouraged, allowing them to meet the clinical needs of patients who need special treatments: drugs no longer available on the market, dosages and/or customized pharmaceutical forms (e.g. pediatric preparations), formulations with appropriate excipients (e.g. intolerances), unstable drugs, associations with several active ingredients.
Veterinary formulations
- consultancy in the definition of the product profile in terms of quality and choice of administration route, but also support and consultancy activities for the preparation of customized preparations, in particular for pets
Bibliographic Analysis and Scientific Dossiers
- Advice is provided for the preparation of scientific dossiers, complete with all the relevant literature in the main biomedical databases and then a thorough bibliographic analysis and the state of the art.
DYSPHARMA
Online support for the correct management of oral drug therapy of patients with swallowing disorders (dysphagia)
Dyspharma is a web-based software that can be used free of charge in reduced form by all platforms with web access, offering a unique solution to prescribers and caregivers involved in the administration of drugs to patients with dysphagia. The platform is periodically updated and is the result of the collaboration of a team of experts in pharmaceutical technology from the University of Camerino with healthcare professionals and IT developers
Food Consulting
Support for the conception, formulation and production of innovative supplements and functional foods.
Consultancy for the design of innovative packaging through the use of biocompatible and biodegradable polymers.
Analysis and in-depth study of the legislative and scientific aspects to aid corporate marketing.
Consultancy for the design of innovative packaging through the use of biocompatible and biodegradable polymers.
Analysis and in-depth study of the legislative and scientific aspects to aid corporate marketing.
Raw materials analysis
- Identification and characterization of raw materials
Nutraceuticals and Supplements Formulation
- Conception, set-up and characterization of innovative formulations
Food formulations
- Development and process support. Product technology characterization
Microbiological analysis
- Microbiological analysis of water intended for human consumption
- Food testing: evaluation of microbiological criteria (indicators) in food products
- Suspension test for chemical disinfectants and antiseptics “Quantitative suspension test for the evaluation of bactericidal activity of chemical disinfectants and antiseptics used in food, industrial, household and community (EN 1276:2009)
- Evaluation of probiotic characteristics of lactic acid bacteria (LAB)
- Antimicrobial activity and antibiotic resistance assays of bacterial strains isolated from different matrices
Bibliographic Analysis and Scientific Dossiers
- Advice is provided for the preparation of scientific dossiers, complete with all the relevant literature in the main biomedical databases and then a thorough bibliographic analysis and the state of the art.
Project Management
Defining the scope of the project
The scope of the project defines its boundaries and serves as the basis for identifying the activities to be done within or outside of it, as well as the amount of work to be completed.
It is necessary to define these objectives with the client to allow them to play an active role in the project, and not just a spectator.
PFC can also create an “ad hoc” Business Plan to evaluate the impact of the project both on already active companies and on Start Up, determining from the beginning the financial requirements and the economic sustainability in the medium and long term.
Definition of the activities to be carried out
It is essential to organize the total scope of each project in a structured way. Its hierarchical structure allows you to identify each “work package” in a simple and intuitive way. These “packages” must have detailed documentation, so that every person involved in the activity can carry them out correctly and efficiently.
Time estimation
The timing or schedule of a project is necessary to better plan its development. Each process must have a start and end date.
Cost monitoring
Controlling project costs in order to complete the work within the assigned budget.
Follow-up is done systematically to avoid delays, make decisions, and take action before costs exceed the budget.
Follow-up e retrospective
During the entire execution of the project, we take care of monitoring the progress, comparing the current progress against the predefined ones, respecting (or not) the terms, costs, scope, etc. So, if necessary, we suggest changes that help improve the efficiency of the project, now and in the future. Managing changes efficiently can make the difference between a successful project or a failure.
Risk management
Each project may present several risks that need to be identified as soon as possible to prevent them from becoming real obstacles during development
